NFL Picks: 2021 Week 3

By Kevin Schroeder
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Updated: September 23, 2021

Last week: 9-7 straight up, 11-5 against the spread, 3-1 best bets, 0-1 lock of the week
Season: 17-15 straight up, 18-14 against the spread, 5-2 best bets, 1-1 lock of the week

Lines for this week’s NFL games come from FanDuel, except for lines marked with an asterisk, which are consensus lines because the game is not on the board at FanDuel at the time of writing. Bold indicates a best bet. Bold and italic indicates the lock of the week.

Away	Line	Home	Straight Up	Against the Spread
Carolina	-7.5	Houston	Carolina	Carolina
Arizona	-7.5	Jacksonville	Arizona	Arizona
Indianapolis	+5	Tennessee	Tennessee	Tennessee
Baltimore	-7.5	Detroit	Baltimore	Baltimore
Washington	+7	Buffalo	Buffalo	Buffalo
New Orleans	+3	New England	New England	New England
Los Angeles Chargers	+6.5	Kansas City	Kansas City	Los Angeles Chargers
Atlanta	+3	New York Giants	New York Giants	New York Giants
Chicago	+7.5	Cleveland	Cleveland	Chicago
Cincinnati	+3	Pittsburgh	Pittsburgh	Cincinnati
Miami	+4.5	Las Vegas	Las Vegas	Las Vegas
New York Jets	+10.5	Denver	Denver	New York Jets
Tampa Bay	-1.5	Los Angeles Rams	Los Angeles Rams	Los Angeles Rams
Seattle	-1.5	Minnesota	Seattle	Seattle
Green Bay	+3	San Francisco	San Francisco	San Francisco
Philadelphia	+3.5	Dallas	Dallas	Dallas